Category Archives: Gene Medicine

Gene therapy may extend life: Study

Researchers in Spain may have discovered the secret to a longer life, a new study says. Continue reading

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Gene Variants That Speed Parkinson's Progression

Researchers may have found a key to determining which Parkinson's disease patients will experience a more rapid decline in motor function, sparking hopes for the development of new therapies and helping identify those who could benefit most from early intervention. Continue reading

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UCLA researchers ID gene variants that speed progression of Parkinson's disease

Public release date: 15-May-2012 [ | E-mail | Share ] Contact: Enrique Rivero erivero@mednet.ucla.edu 310-794-2273 University of California – Los Angeles Health Sciences UCLA researchers may have found a key to determining which Parkinson’s disease patients will experience a more rapid decline in motor function, sparking hopes for the development of new therapies and helping identify those who could benefit most from early intervention. In a study published May 15 in the peer-reviewed online journal PLoS ONE, the researchers found that Parkinson’s sufferers who possess two specific variants of a gene known to be a risk factor for the disease had a significantly speedier progression toward motor decline than patients without these variants. “This is a relatively small study, with 233 patients, but the effects we’re seeing are actually quite large,” said Dr. Continue reading

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First gene therapy successful against aging-associated decline: Mouse lifespan extended up to 24% with a single …

ScienceDaily (May 14, 2012) A new study consisting of inducing cells to express telomerase, the enzyme which — metaphorically — slows down the biological clock — was successful. The research provides a “proof-of-principle” that this “feasible and safe” approach can effectively “improve health span.” A number of studies have shown that it is possible to lengthen the average life of individuals of many species, including mammals, by acting on specific genes. To date, however, this has meant altering the animals’ genes permanently from the embryonic stage — an approach impracticable in humans. Continue reading

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Gene Predicts Parkinson's Progression

Diane Cook’s 65th birthday was a milestone for her, but not because of her age. That was the day she was diagnosed with Parkinson’s disease Continue reading

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Gene variants that speed progression of Parkinson's disease identified

Washington, May 16 (ANI): A new discovery may hold the key to determine which Parkinson's disease patients will experience a more rapid decline in motor function, sparking hopes for the development of new therapies and helping identify those who could benefit most from early intervention. Continue reading

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Gene therapy extends mouse lifespan by 24 pc

Washington, May 15 (ANI): Scientists have successfully extended the lifespan of mice using gene therapy, a strategy never before employed to combat ageing. Continue reading

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Cardium Reports New Catheter-Based Methods Significantly Boost Cardiac Gene Delivery In Late-Breaking Presentation at …

SAN DIEGO, May 16, 2012 /PRNewswire/ — Cardium Therapeutics (CXM) today announced a late-breaking poster presentation at the American Society of Gene & Cell Therapy (ASGCT) 15th Annual Meeting being held May 16-19, 2012 at the Pennsylvania Convention Center in Philadelphia, PA. (Photo: http://photos.prnewswire.com/prnh/20120516/LA07787) (Logo: http://photos.prnewswire.com/prnh/20051018/CARDIUMLOGO) The new research findings demonstrate that cardiac ischemia plays an important role in adenovector gene transfection (delivery) in mammalian hearts Continue reading

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Mystery gene reveals new mechanism for anxiety disorders

ScienceDaily (May 15, 2012) A novel mechanism for anxiety behaviors, including a previously unrecognized inhibitory brain signal, may inspire new strategies for treating psychiatric disorders, University of Chicago researchers report. By testing the controversial role of a gene called Glo1 in anxiety, scientists uncovered a new inhibitory factor in the brain: the metabolic by-product methylglyoxal. The system offers a tantalizing new target for drugs designed to treat conditions such as anxiety disorder, epilepsy, and sleep disorders. Continue reading

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Strong Medicine ”Temperature’s Rising” 1/2 – Video


14-05-2012 16:11 I DO NOT OWN THIS SHOW S04E08 Temperature’s Rising As a heat wave hits Philadelphia, Andy and the staff will need to get used to its disaster plan to cope with heat wave. Claire, a patient of Dr. Continue reading

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Results from Two Studies Demonstrate the Clinical Utility of CardioDx Gene Expression Test in Patients with Suspected …

PALO ALTO, Calif.–(BUSINESS WIRE)– CardioDx, Inc., a pioneer in the field of cardiovascular genomic diagnostics, today announced results of two studies evaluating the role of the Corus CAD gene expression test in clinical decision-making for the evaluation of patients with suspected obstructive coronary artery disease (CAD). Results were presented last week at the Quality of Care and Outcomes Research (QCOR) 2012 Scientific Session in Atlanta, Ga., and the Society of General Internal Medicine (SGIM) 35th Annual Meeting in Orlando, Fla. Every day, thousands of patients visit a primary care physician for symptoms suggestive of coronary artery disease an enormous cost to the health care system, said David Levison, president and CEO of CardioDx Continue reading

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CNIO scientists successfully test the first gene therapy against aging-associated decline

Public release date: 14-May-2012 [ | E-mail | Share ] Contact: Juan J. Gomez juanj.gomez@cnio.es 34-917-328-000-4060 Centro Nacional de Investigaciones Oncologicas (CNIO) A number of studies have shown that it is possible to lengthen the average life of individuals of many species, including mammals, by acting on specific genes. Continue reading

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Gene Expression Analysis with Apple's iOS

The latest in a growing number of efforts aimed at exploiting mobile app technology for life sciences research, a group at Baylor College of Medicine has developed a prototype app for displaying gene expression data using Apple’s iOS mobile operating system. The group, led by Baylor’s Chad Shaw, describe their new mobile “Hematopoietic Expression Viewer” app in a paper published online last week in the journal Bioinformatics. Continue reading

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Researchers use light to switch on gene expression

Public release date: 10-May-2012 [ | E-mail | Share ] Contact: Tracey Peake tracey_peake@ncsu.edu 919-515-6142 North Carolina State University Imagine being able to control genetic expression by flipping a light switch. Researchers at North Carolina State University are using light-activated molecules to turn gene expression on and off. Their method enables greater precision when studying gene function, and could lead to targeted therapies for diseases like cancer. Continue reading

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Gene therapy for hearing loss: Potential and limitations

Public release date: 11-May-2012 [ | E-mail | Share ] Contact: Quinn Eastman qeastma@emory.edu 404-727-3990 Emory University Regenerating sensory hair cells, which produce electrical signals in response to vibrations within the inner ear, could form the basis for treating age- or trauma-related hearing loss. One way to do this could be with gene therapy that drives new sensory hair cells to grow Continue reading

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CardioDx to Present Results from Two Studies Evaluating the Clinical Utility of a Gene Expression Test for Obstructive …

PALO ALTO, Calif.–(BUSINESS WIRE)– CardioDx, Inc., a pioneer in the field of cardiovascular genomic diagnostics, today announced that data from two studies evaluating the effect of the Corus CAD gene expression test on clinician decision-making for patients with suspected obstructive coronary artery disease will be presented at two upcoming conferences. On Wednesday, May 9, from 5:00 to 6:30 p.m. ET, John McPherson, M.D., director of the Cardiovascular Intensive Care Unit at Vanderbilt University Medical Center, in Nashville, Tenn., will present Improved Diagnostic Work-up of Patients Presenting to the Cardiologist with Symptoms of Suspected Obstructive Coronary Artery Disease: Results from the IMPACT (Investigation of a Molecular PersonalizedCoronary Gene Expression Test on Cardiology Practice Pattern) Trial at the Quality of Care and Outcomes Research (QCOR) 2012 Scientific Sessions, which will be held May 9-11, 2012, at the Omni Hotel at CNN Center in Atlanta, Ga. Continue reading

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Defective carnitine metabolism may play role in autism

Public release date: 7-May-2012 [ | E-mail | Share ] Contact: Glenna Picton picton@bcm.edu 713-798-4710 Baylor College of Medicine HOUSTON — (May 7, 2012) The deletion of part of a gene that plays a role in the synthesis of carnitine an amino acid derivative that helps the body use fat for energy may play a role in milder forms of autism, said a group of researchers led by those at Baylor College of Medicine (http://www.bcm.edu) and Texas Children’s Hospital (http://www.texaschildrens.org). “This is a novel inborn error of metabolism,” said Dr Continue reading

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Repost: Depressed mice, gene therapy, and p11

Todays post is a repost from October 2010. Continue reading

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New Tanenbaum Centre for Pharmacogenetics to accelerate gene-based personalized medicine in psychiatry

$19 million collaboration fuelling groundbreaking discoveries TORONTO, May 7, 2012 /CNW/ – Lawrence Tanenbaum, O.C., along with his wife Judy Tanenbaum, today joined the Honourable Brad Duguid Minister of Economic Development and Innovation, renowned researcher Dr. Continue reading

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Gene points to Achilles' heel in MRSA superbug

Asian outbreaks of a notorious antibiotic-resistant super-germ are being driven by a gene that helps the bug colonise the nostrils, lungs and skin and evade the immune defences, scientists said on Sunday.Source:http://news.search.yahoo.com/news/rss?p=gene+medicine&ei=UTF-8&fl=0&x=wrt

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