Category Archives: Molecular Genetics

Abbott to Collaborate on Rapid Molecular Test to Identify Serious Infections in Bones and Joints

ABBOTT PARK, Ill., March 5, 2012 /PRNewswire/ –Abbott(NYSE: ABT – News) announced today it will collaborate with Genetics Laboratory, Inc. (GenLab) on the development of a molecular diagnostic test that will be designed to rapidly detect microorganisms that cause orthopedic infections. Under terms of the agreement, Abbott, in conjunction with GenLab, will develop and commercialize the new assay for use on the PLEX-ID automated microbial identification system Continue reading

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Atossa Genetics Lab Gains CLIA Certification

By a GenomeWeb staff reporter NEW YORK (GenomeWeb News) Breast cancer diagnostics developer Atossa Genetics said today that its breast health reference lab has received Clinical Laboratory Improvement Amendments certification from the Centers for Medicare and Medicaid Services. The company’s National Reference Laboratory for Breast Health subsidiary, located in Seattle, was certified after an inspection of its facilities, processes, and personnel, and a review of the validation and clinical reports from its lab-developed tests, and the ForeCyte and ArgusCyte Breast Health Tests. The company’s tests use molecular and cellular biomarkers for breast cancer risk, and are based on its Mammary Aspirate Specimen Cytology system, which enables nurses or physician assistants to collect samples in around 10 minutes Continue reading

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Abbott Molecular President Stafford O'Kelly to Deliver Opening Keynote at MDx NEXT in Boston

PETERBOROUGH, NH–(Marketwire -03/05/12)- G2 Intelligence announced today that Stafford O’Kelly, President of Abbott Molecular and Chair of the Personalized Medicine Coalition, will deliver the opening keynote address, “Putting Molecular Diagnostics to Work: What’s Now and What’s Next,” at MDx NEXT, G2 Intelligence’s seventh annual molecular diagnostics conference. “With his depth and breadth of experience in this rapidly growing area of testing, Stafford O’Kelly is an exciting addition to our agenda,” said Stephanie Murg, Managing Director of G2 Intelligence and MDx NEXT Program Chair. “Labs who want to add molecular diagnostics or optimize their current offerings will benefit enormously from Mr. Continue reading

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Nationwide Children's Hospital neuromuscular disorder podcasts now available on iTunes

( Nationwide Children's Hospital ) In 2010, the Center for Gene Therapy at Nationwide Children's Hospital launched a monthly podcast entitled, "This Month in Muscular Dystrophy," featuring internationally known scientists discussing the latest research in muscular dystrophy and other neuromuscular … Continue reading

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Natural Molecular Testing Corp. (NMTC) Names Karthikeshwar Kasirajan, M.D., as Chief Medical Officer

SEATTLE–(BUSINESS WIRE)– Natural Molecular Testing Corp. (NMTC), a company providing groundbreaking clinical molecular testing and services in the medical genomics field, today announced that Karthikeshwar Kasirajan, M.D., has joined the company as Chief Medical Officer. Continue reading

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CombiMatrix Corporation Reports Fourth Quarter 2011 Financial Results

IRVINE, Calif., Feb. 29, 2012 (GLOBE NEWSWIRE) — CombiMatrix Corporation (Nasdaq:CBMX – News), a molecular diagnostics company performing DNA-based testing services for cancer and developmental disorders, reported today that total revenues for the fourth quarter of 2011 increased 52% to $1.2 million from $804,000 in the fourth quarter of 2010. Continue reading

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Faulty genetics not at fault

By Joy Shan Contributing Reporter Tuesday, February 28, 2012 Suganthi Balasubramanian, associate research scientist in Mark Gersteins lab in Yales Molecular Biophysics and Biochemistry Department, was the lead Yale author in a paper published in the Feb. 17 issue of Science as part of a collaborative effort called the 1000 Genomes Project Continue reading

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Cancer Commons Researchers Publish Molecular Disease Model for Lung Cancer

PALO ALTO, Calif.–(BUSINESS WIRE)– Cancer Commons, an openscience initiative to personalize cancer treatments and accelerate research, announces the publication of a molecular disease model (MDM) for lung cancer. The paper, by Lisandra West, Ravi Salgia, and others will appear in the February 21st issue of PLoS ONE (http://www.plosone.org) Continue reading

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Renato Dulbecco obituary

Nobel prize-winning virologist who recognised the role of molecular genetics in cancer research The virologist and molecular geneticist Renato Dulbecco, who has died aged 97, unravelled the way in which cancer-causing viruses either transform or replicate in their host cells. … Continue reading

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GQ-Dx 2.0 Helps Laboratories Deliver Fast, Accurate, and Actionable NGS Diagnostics to the Clinic

WESTBOROUGH, Mass.–(BUSINESS WIRE)– GenomeQuest Inc., a global provider of large-scale genomic software applications, today introduced new enhancements to its GQ-Dx genomic decision support system that enables molecular laboratories to produce routine, actionable diagnostic reports from next generation sequencing (NGS) runs. Highlighted by a proprietary genomic knowledge engine, GQ-Dx 2.0 transforms NGS diagnostics from slow, labor-intensive odysseys into daily, healthcare operations. As a result, healthcare professionals can now offer this new generation of diagnostics to patients today Continue reading

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Research and Markets: Molecular Tools and Infectious Disease Epidemiology

DUBLIN–(BUSINESS WIRE)– Research and Markets (http://www.researchandmarkets.com/research/897dee/molecular_tools_an) has announced the addition of Elsevier Science and Technology's new report “Molecular Tools and Infectious Disease Epidemiology” to their offering. Continue reading

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B.C. specialist says more guns needed in the chemotherapy artillery

We’ve heard about biological smart bombs in the war on cancer. Now we’re going to start hearing about the pressing need for more diffuse bombs in the chemotherapy artillery cabinet. Continue reading

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Molecular Biology


30-01-2012 03:16 Fingerprints from the past and prospects for the future” Continue reading

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Common flame retardant linked to social, behavioral and learning deficits

Public release date: 16-Feb-2012 [ | E-mail | Share ] Contact: Phyllis Brown phyllis.brown@ucdmc.ucdavis.edu 916-734-9023 University of California – Davis Health System Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning and long-term memory when compared with the offspring of normal unexposed mice, a study by researchers at UC Davis has found. The researchers said the study is the first to link genetics and epigenetics with exposure to a flame retardant chemical Continue reading

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Not-So-Fictional Yeast Genetics

Leonard, one of the characters in Jeffrey Eugenides' novel The Marriage Plot, set in the 1980s, is a biologist studying yeast genetics. In the book, Leonard's description of his work brought back memories for NIH's Amar Klar, reports The New York Times. “The detailed description was of his own work Continue reading

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Smithsonian to Sequence Animal and Plant Pathogens on GS Junior

The Smithsonian Conservation Biology Institute in Washington, DC, said this week that it will use Roche's 454 GS Junior sequencing system for research projects in animal disease resistance, population genetics, and molecular ecology in the institute's Center for Conservation and Evolutionary Genetics. Continue reading

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DuPont to Establish Molecular Breeding Technology Hub in China

DES MOINES, Iowa and BEIJING, Feb. 14, 2012 /PRNewswire/ – DuPont has signed a multi-year lease agreement with Beijing International Flower Port to build a state-of-the-art Technology Hub for its Pioneer seed business in Beijing, China.  The new facility is slated to open later this year and will employ nearly 50 researchers.  The Technology Hub will use Pioneer's global capabilities in molecular breeding to develop new high-yielding maize hybrids which will improve the sustainability of farming in China, while enhancing food security.   The Technology Hub will leverage Pioneer's proprietary matrix of molecular breeding technologies called the Accelerated Yield Technology (AYT™) system.  The AYT™ system uses doubled haploids, laser assisted seed selection, precision phenotyping methods and other leading technologies to identify superior gene combinations earlier in the breeding process compared to traditional methods alone.  The Technology Hub is the latest addition to DuPont's growing R&D network in China.  For example, Pioneer has seven other research locations and a research joint venture established in 2007 with Sino Bioway Group Co., Ltd., a Peking University bio-agriculture company, known as Beijing Kaituo DNA (KTDNA) Biotech Research Center Co., Ltd. “This is a further extension of how DuPont is investing in global science to identify solutions locally,” said William S. Continue reading

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Author of Nationwide, NIH-Sponsored Study Endorses Microarray Testing as Preferred Standard of Care for Pre-Natal …

IRVINE, Calif., Feb. 13, 2012 (GLOBE NEWSWIRE) — CombiMatrix Corporation (Nasdaq:CBMX – News), a molecular diagnostics company performing DNA-based testing services for cancer and developmental disorders, today announced that one of the nation's leading clinicians in the field of reproductive genetics has called for chromosomal microarray testing to replace karyotyping, the historic practice, as the standard of care for prenatal testing. CombiMatrix is one of the few independent companies that specialize in chromosomal microarray testing (CMA), the primary genetic test to evaluate newborns with birth defects but has not routinely been used for prenatal testing. Continue reading

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Research and Markets: Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 2nd Edition

DUBLIN–(BUSINESS WIRE)– Research and Markets (http://www.researchandmarkets.com/research/0e72cb/neurodegeneration) has announced the addition of John Wiley and Sons Ltd's new book “Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 2nd Edition” to their offering. Continue reading

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Eulogy for a brilliant mentor and teacher

Here is a eulogy for a pioneering scientist that says more about the lifelong effects of a dynamic teacher on his students than any “value-added” formula ever could. The eulogy was delivered by Jeffrey Ravetch, head of the Leonard Wagner Laboratory of Molecular Genetics and Immunology at Rockefeller University in New York, at a memorial service last week for his former teacher and mentor, Norton Zinder, a ground-breaking geneticist and microbiologist. Zinder, who was my brother-in-law’s father, died this month at age 83 Continue reading

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